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Modifications on the Tetrahydroquinoline Scaffold Targeting a Phenylalanine Cluster on GPER as Antiproliferative Compounds against Renal, Liver and Pancreatic Cancer Cells David Méndez-Luna, Loreley Araceli Morelos-Garnica, Juan Benjamín García-Vázquez, Martiniano Bello, Itzia Irene Padilla-Martínez, Manuel Jonathan Fragoso-Vázquez, Alfonso Dueñas González, Nuria De Pedro, José Antonio Gómez-Vidal, Humberto Lubriel Mendoza-Figueroa, José Correa-Basurto Pharmaceuticals (Basel) 2021 Jan; 14(1): 49. Published online 2021 Jan 10. doi: 10.3390/ph14010049 PMCID: PMC7826836
Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Nawaf A. AlSaif, Mohammed M. Alanazi, Manal A. El-Gendy, Ahmad J. Obaidullah, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Ibrahim A. Al-Suwaidan J Enzyme Inhib Med Chem. 2020; 35(1): 610–621. Published online 2020 Feb 3. doi: 10.1080/14756366.2020.1722120 PMCID: PMC7034070
The association of tryptophan and phenylalanine are associated with arsenic-induced skin lesions in a Chinese population chronically exposed to arsenic via drinking water: a case–control study Yaping Wei, Chaonan Jia, Yuan Lan, Xiangqing Hou, Jingjing Zuo, Jushuang Li, Tao Wang, Guangyun Mao BMJ Open. 2019; 9(10): e025336. Published online 2019 Oct 30. doi: 10.1136/bmjopen-2018-025336 PMCID: PMC6830718
Performance of laboratory tests used to measure blood phenylalanine for the monitoring of patients with phenylketonuria Stuart J. Moat, Danja Schulenburg-Brand, Hugh Lemonde, James R. Bonham, Cas W. Weykamp, Joanne V. Mei, Graham S. Shortland, Rachel S. Carling J Inherit Metab Dis. Author manuscript; available in PMC 2021 Mar 15.Published in final edited form as: J Inherit Metab Dis. 2020 Mar; 43(2): 179–188. Published online 2019 Oct 2. doi: 10.1002/jimd.12163 PMCID: PMC7957320
The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture System Stefania Pagani, Manuela Minguzzi, Laura Sicuro, Francesca Veronesi, Spartaco Santi, Anna Scotto D’Abusco, Milena Fini, Rosa Maria Borzì Sci Rep. 2019; 9: 13603. Published online 2019 Sep 19. doi: 10.1038/s41598-019-49188-9 PMCID: PMC6753094
Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion Nyah Rodman, Jasmine Martinez, Sammie Fung, Jun Nakanouchi, Amber L. Myers, Caitlin M. Harris, Emily Dang, Jennifer S. Fernandez, Christine Liu, Anthony M. Mendoza, Veronica Jimenez, Nikolas Nikolaidis, Catherine A. Brennan, Robert A. Bonomo, Rodrigo Sieira, Maria Soledad Ramirez Front Microbiol. 2019; 10: 1581. Published online 2019 Jul 17. doi: 10.3389/fmicb.2019.01581 PMCID: PMC6650585
STEM-22. UPTAKE OF P-BORONO-PHENYLALANINE BY BRAIN TUMOR STEM LIKE CELLS ANALYZED BY MASS CYTOMETRY Natsuko Kondo, Masaki HIkida, Mitsutoshi Nakada, Minoru Suzuki Neuro Oncol. 2018 Nov; 20(Suppl 6): vi248. Published online 2018 Nov 5. doi: 10.1093/neuonc/noy148.1029 PMCID: PMC6216218
PLASMA PHENYLALANINE DETERMINATION BY QUANTITATIVE DENSITOMETRY OF THIN LAYER CHROMATOGRAMS AND BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY IN RELATION WITH MODERN MANAGEMENT OF PHENYLKETONURIA C.V. Mihali, C.M. Petrescu, F.C. Ladaşiu-Ciolacu, I. Mândruţiu, D. Bechet, T. Nistor, A. Ardelean, Gh. Benga Acta Endocrinol (Buchar) 2018 Oct-Dec; 14(4): 556–561. doi: 10.4183/aeb.2018.556 PMCID: PMC6516402
Evaluation of D-isomers of 4-borono-2-18F-fluoro-phenylalanine and O-11C-methyl-tyrosine as brain tumor imaging agents: a comparative PET study with their L-isomers in rat brain glioma Masakatsu Kanazawa, Shingo Nishiyama, Fumio Hashimoto, Takeharu Kakiuchi, Hideo Tsukada EJNMMI Res. 2018; 8: 47. Published online 2018 Jun 13. doi: 10.1186/s13550-018-0404-6 PMCID: PMC5999598
Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis Geraldine Gueron, Nicolás Anselmino, Paula Chiarella, Emiliano G. Ortiz, Sofia Lage Vickers, Alejandra V. Paez, Jimena Giudice, Mario D. Contin, Daiana Leonardi, Felipe Jaworski, Verónica Manzano, Ariel Strazza, Daniela R. Montagna, Estefania Labanca, Javier Cotignola, Norma D´Accorso, Anna Woloszynska-Read, Nora Navone, Roberto P. Meiss, Raúl Ruggiero, Elba Vazquez Cell Death Dis. 2018 Feb; 9(2): 140. Published online 2018 Feb 2. doi: 10.1038/s41419-017-0147-8 PMCID: PMC5833805
Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice Shelley R Winn, Tanja Scherer, Beat Thöny, Ming Ying, Aurora Martinez, Sydney Weber, Jacob Raber, Cary O Harding Mol Genet Metab. Author manuscript; available in PMC 2019 Jan 1.Published in final edited form as: Mol Genet Metab. 2018 Jan; 123(1): 6–20. Published online 2017 Oct 19. doi: 10.1016/j.ymgme.2017.10.009 PMCID: PMC5786171
COMPARISON OF PLASMA PHENYLALANINE DETERMINATION BY DENSITOMETRY OF THIN-LAYER CHROMATOGRAMS AND BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY IN RELATION WITH THE SCREENING OF PHENYLKETONURIA C.V. Mihali, M.C. Petrescu, I. Mândruţiu, D. Bechet, T.V. Nistor, V. Turcuş, A. Ardelean, Gh. Benga Acta Endocrinol (Buchar) 2017 Apr-Jun; 13(2): 203–208. doi: 10.4183/aeb.2017.203 PMCID: PMC6516440
Regulation of plant immune receptor accumulation through translational repression by a glycine-tyrosine-phenylalanine (GYF) domain protein Zhongshou Wu, Shuai Huang, Xiaobo Zhang, Di Wu, Shitou Xia, Xin Li eLife. 2017; 6: e23684. Published online 2017 Mar 31. doi: 10.7554/eLife.23684 PMCID: PMC5403212
Estimation of optimal ratios of digestible phenylalanine + tyrosine, histidine, and leucine to digestible lysine for performance and breast yield in broilers Sebastian M. Franco, Fernando de C. Tavernari, Rosana C. Maia, Victor R. S. M. Barros, Luiz F. T. Albino, Horacio S. Rostagno, Guilherme R. Lelis, Arele A. Calderano, Ryan Neil Dilger Poult Sci. 2017 Apr; 96(4): 829–837. Published online 2016 Sep 19. doi: 10.3382/ps/pew305 PMCID: PMC5444564
Self-assembled micelles of amphiphilic poly(l-phenylalanine)-b-poly(l-serine) polypeptides for tumor-targeted delivery Ziming Zhao, Yu Wang, Jin Han, Keli Wang, Dan Yang, Yihua Yang, Qian Du, Yuanjian Song, Xiaoxing Yin Int J Nanomedicine. 2014; 9: 5849–5862. Published online 2014 Dec 12. doi: 10.2147/IJN.S73111 PMCID: PMC4270381
Immune Activation and Inflammation in Patients with Cardiovascular Disease Are Associated with Higher Phenylalanine to Tyrosine Ratios: The Ludwigshafen Risk and Cardiovascular Health Study Christian Murr, Tanja B. Grammer, Andreas Meinitzer, Marcus E. Kleber, Winfried März, Dietmar Fuchs J Amino Acids. 2014; 2014: 783730. Published online 2014 Feb 10. doi: 10.1155/2014/783730 PMCID: PMC3934657
Possible association between common variants of the phenylalanine hydroxylase (PAH) gene and memory ' performance in healthy adults Toshiya Teraishi, Daimei Sasayama, Hiroaki Hori, Noriko Yamamoto, Takashi Fujii, Junko Matsuo, Anna Nagashima, Yukiko Kinoshita, Kotaro Hattori, Miho Ota, Sayaka Fujii, Hiroshi Kunugi Behav Brain Funct. 2013; 9: 30. Published online 2013 Jul 30. doi: 10.1186/1744-9081-9-30 PMCID: PMC3733818
Radiosynthesis and Biological Evaluation of alpha-[F-18]Fluoromethyl Phenylalanine for Brain Tumor Imaging Chaofeng Huang, Liya Yuan, Keith Rich, Jonathan McConathy Nucl Med Biol. Author manuscript; available in PMC 2014 May 1.Published in final edited form as: Nucl Med Biol. 2013 May; 40(4): 498–506. Published online 2013 Mar 23. doi: 10.1016/j.nucmedbio.2012.12.013 PMCID: PMC3644424
Comparison of Growth Performance and Whole-body Amino Acid Composition in Red Seabream (Pagrus major) Fed Free or Dipeptide Form of Phenylalanine Sung-Sam Kim, Samad Rahimnejad, Jin-Woo Song, Kyeong-Jun Lee Asian-Australas J Anim Sci. 2012 Aug; 25(8): 1138–1144. doi: 10.5713/ajas.2012.12054 PMCID: PMC4092991
Mannose 6-Phosphate Conjugation Is Not Sufficient to Allow Induction of Immune Tolerance to Phenylalanine Ammonia-Lyase in Dogs Moin Vera, Thomas Lester, Bin Zhao, Pascale Tiger, Scott Clarke, Brigette L. Tippin, Merry B. Passage, Steven Q. Le, Javier Femenia, Jeffrey F. Lemontt, Emil D. Kakkis, Patricia I. Dickson JIMD Rep. 2013; 8: 63–72. Published online 2012 Jul 6. doi: 10.1007/8904_2012_162 PMCID: PMC3565636
Monocytes and neutrophils from tuberculosis patients are insensitive to anti-inflammatory effects triggered by the prototypic formyl peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) M BEIGIER-BOMPADRE, M ALEMÁN, P BARRIONUEVO, M C FRANCO, C J RUBEL, M Del C SASIAIN, M S PALERMO, E ABBATE, M A ISTURIZ Clin Exp Immunol. 2003 Aug; 133(2): 267–274. doi: 10.1046/j.1365-2249.2003.02212.x PMCID: PMC1808772
Activation of methotrexate-phenylalanine by monoclonal antibody--carboxypeptidase A conjugate for the specific treatment of ovarian cancer in vitro. M. J. Perron, M. Page Br J Cancer. 1996 Feb; 73(3): 281–287. doi: 10.1038/bjc.1996.50 PMCID: PMC2074434
Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl- phenylalanine J Exp Med. 1995 May 1; 181(5): 1763–1772. doi: 10.1084/jem.181.5.1763 PMCID: PMC2191980
Characteristics of oedema formation induced by N-formyl-methionyl-leucyl-phenylalanine in rabbit skin. P. G. Hellewell, H. Yarwood, T. J. Williams Br J Pharmacol. 1989 May; 97(1): 181–189. doi: 10.1111/j.1476-5381.1989.tb11940.x PMCID: PMC1854467
Genetic control of major histocompatibility complex-linked immune responses to synthetic polypeptides in man: poly(L-phenylalanine, L-glutamic acid)-poly (DL-alanine)--poly(L-lysine) and L-glutamic acid, L-alanine, L-tyrosine (60:30:10). M M Chan, W B Bias, S H Hsu, D A Meyers Proc Natl Acad Sci U S A. 1984 Jun; 81(11): 3521–3525. doi: 10.1073/pnas.81.11.3521 PMCID: PMC345540
Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen. G Carmichael, B S Schaffhausen, G Mandel, T J Liang, T L Benjamin Proc Natl Acad Sci U S A. 1984 Feb; 81(3): 679–683. doi: 10.1073/pnas.81.3.679 PMCID: PMC344898
Lysosomal enzyme release from leucocytes by N-formyl-L-methionyl-L-leucyl-L-phenylalanine in vitro: effect of some anti-inflammatory drugs [proceedings] R M Palmer, M Weatherall Br J Pharmacol. 1978 Mar; 62(3): 421P–422P. PMCID: PMC1668185
The immune response of allophenic mice to the synthetic polymer L-glutamic acid, L-lysine, L-phenylalanine. II. Lack of gene complementation in two nonresponder strains CM Warner, JL McIvor, PH Maurer, CF Merryman J Exp Med. 1977 Mar 1; 145(3): 766–771. doi: 10.1084/jem.145.3.766 PMCID: PMC2180709
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