Periostin (POSTN, PN, or osteoblast-specific factor OSF-2) is a protein that in humans is encoded by the POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells. Periostin is a gla domain vitamin K dependent factor.
In human anatomy, a hamstring (/ˈhæmstrɪŋ/) is any one of the three posterior thigh muscles in between the hip and the knee (from medial to lateral: semimembranosus , semitendinosus and biceps femoris ). The hamstrings are susceptible to injury. In quadrupeds, the hamstring is the single large tendon found behind the knee or comparable area.