Skip to main content

Renin

 

Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid) and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.

Renin is not commonly referred to as a hormone, albeit it having a receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor (see also below), as well as enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I.

Labels:

Popular posts from this blog

ornithine

Related Articles Oxidative ornithine metabolism supports non-inflammatory C. difficile colonization Kali M. Pruss, Fatima Enam, Eric Battaglioli, Mary DeFeo, Oscar R. Diaz, Steven K. Higginbottom, Curt R. Fischer, Andrew J. Hryckowian, William Van Treuren, Dylan Dodd, Purna Kashyap, Justin L. Sonnenburg Nat Metab. 2022; 4(1): 19–28. Published online 2022 Jan 6. doi: 10.1038/s42255-021-00506-4 PMCID: PMC8803604 Longitudinal Metabolomics Reveals Ornithine Cycle Dysregulation Correlates With Inflammation and Coagulation in COVID-19 Severe Patients Tao Li, Nianzhi Ning, Bo Li, Deyan Luo, Enqiang Qin, Wenjing Yu, Jianxin Wang, Guang Yang, Nan Nan, Zhili He, Ning Yang, Saisai Gong, Jiajia Li, Aixia Liu, Yakun Sun, Zhan Li, Tianye Jia, Jie Gao, Wang Zhang, Yanyu Huang, Jun Hou, Ying Xue, Deyu Li, Zhen Wei, Liangyan Zhang, Boan Li, Hui Wang Front Microbiol. 2021; 12: 723818. Published online 2021 Dec 3. doi: 10.3389/fmicb.2021.723818 PMCID: PMC8678452 Dual Inhi...
Read more

Limosilactobacillus

  Limosilactobacillus is a thermophilic and heterofermentative genus of lactic acid bacteria created in 2020 by splitting from Lactobacillus. The name is derived from the Latin limosus "slimy", referring to the property of most strains in the genus to produce exopolysaccharides from sucrose. The genus currently includes 31 species or subspecies, most of these were isolated from the intestinal tract of humans or animals. Limosilactobacillus reuteri has been used as a model organism to evaluate the host-adaptation of lactobacilli to the human and animal intestine and for the recruitment of intestinal lactobacilli for food fermentations. Limosilactobacilli are heterofermentative and produce lactate, CO2, and acetate or ethanol from glucose; several limosilactobacilli, particularly strains of Lm. reuteri convert glycerol or 1,2-propanediol to 1,3 propanediol or propanol, respectively. Most strains do not grow in presence of oxygen, or in de Man, Rogosa Sharpe (MRS) mediu...
Read more

Hamstring

In human anatomy, a hamstring (/ˈhæmstrɪŋ/) is any one of the three posterior thigh muscles in between the hip and the knee (from medial to lateral: semimembranosus , semitendinosus and biceps femoris ). The hamstrings are susceptible to injury. In quadrupeds, the hamstring is the single large tendon found behind the knee or comparable area.
Read more

Lactococcus lactis

  Lactococcus lactis is a Gram-positive bacterium used extensively in the production of buttermilk and cheese, but has also become famous as the first genetically modified organism to be used alive for the treatment of human disease. L. lactis cells are cocci that group in pairs and short chains, and, depending on growth conditions, appear ovoid with a typical length of 0.5 - 1.5 µm. L. lactis does not produce spores (nonsporulating) and are not motile (nonmotile). They have a homofermentative metabolism, meaning they produce lactic acid from sugars. They've also been reported to produce exclusive L-(+)-lactic acid. However, reported D-(−)-lactic acid can be produced when cultured at low pH. The capability to produce lactic acid is one of the reasons why L. lactis is one of the most important microorganisms in the dairy industry. Based on its history in food fermentation, L. lactis has generally recognized as safe (GRAS) status, with few case reports of it being an opportuni...
Read more